PGD: PRE IMPLANTATION GENETIC

PGD:PRE IMPLANTATION GENETIC

PGD – Enhancing Genetic Health through PreImplantation Genetic Diagnosis atSwetcha hospital

Preimplantation genetic diagnosis (PGD) stands as a critical procedure conducted before embryo implantation, aimed at identifying genetic anomalies within embryos created through the process of InVitro Fertilization (IVF). This innovative technique plays a pivotal role in preventing the transmission of certain hereditary diseases or disorders to the offspring.

PGD is carried out as a meticulous testing process on embryos generated during an IVF treatment cycle, specifically targeting genetic disorders. The procedure involves the removal and evaluation of cells from the embryos to ascertain the presence of problematic genes, ensuring a comprehensive assessment before transferring embryos to the uterus.

Several human diseases, including Huntington's disease, Neurofibromatosis, Cystic Fibrosis, and SickleCell Anemia, are caused by single gene mutations. Presently, PGD is available for a wide spectrum of single gene disorders.

The Mechanism of PGD:

1. IVF Process: The journey of PreImplantation Genetic Diagnosis begins with IVF, encompassing egg retrieval and fertilization within a laboratory setting. Subsequent to successful fertilization, the embryo divides into eight cells over the course of three days.
2. PGD Steps: The key stages of PGD involve:
   • Extraction: One or two cells are extracted from the embryo.
   • Evaluation: The extracted cells are meticulously assessed to identify the presence of problematic genes.

Once the PGD procedure is completed, embryos devoid of genetic issues are transferred to the women's uterus, aiming for successful implantation. Embryos free from problems are cryopreserved for potential future use, while embryos bearing problematic genes are not utilized.

The Advantages of PGD:

• Offers couples at high risk of passing on inherited disorders a significantly higher chance of achieving an unaffected pregnancy.
• Reduces the likelihood of detecting an affected fetus during prenatal testing, alleviating the complex decisionmaking process regarding pregnancy termination.

Who Can Benefit from PGD?

Couples who:

• Are aware of their status as carriers of a significant inherited condition.
• Are afflicted by a genetic disease with a known mutation.

These couples can avail expert genetic counseling at Swetcha hospital, a prestigious Fertility Centre in Kakinada. The collaboration between Fertility Specialists and the scientific team at Swetcha hospital will determine the suitability of PGD.

It's essential to acknowledge that while genetic screening is invaluable, it's not infallible. Therefore, genetic screening conducted at Swetcha hospital, led by top fertility specialists in Kakinada and India, should be followed by prenatal testing for confirmation. This step ensures accurate genetic diagnosis and the evaluation of whether the fetus remains unaffected by the specific disease or mutation.

For exceptional PreImplantation Genetic Diagnosis (PGD) services in Kakinada,Swetcha hospital emerges as the prime choice, exemplifying excellence in the realm of fertility clinics.